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mTOR Inhibitor, Ku-0063794
A mTOR inhibitor
Product Overview
Product Name: mTOR Inhibitor, Ku-0063794
Alternate Name/Synonyms: rel-5-[2-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol
Description: A potent mTOR (mammalian target of rapamycin) inhibitor (IC₅₀ = ~10 nM for mTORC1 and mTORC2, respectively). Displays no activity against PI 3-kinase or 76 other kinases tested.
Peptide Sequence: N/A
Appearance: Pale yellow solid
Formulation: N/A
CAS Number: 938440-64-3
Molecular Formula: C₂₅H₃₁N₅O₄
Molecular Weight: 465.54
Purity: ≥98% by HPLC
Solubility:DMSO
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: CC1CN(CC(O1)C)C2=NC3=C(C=CC(=N3)C4=CC(=C(C=C4)OC)CO)C(=N2)N5CCOCC5
InChi: InChI=1S/C25H31N5O4/c1-16-13-30(14-17(2)34-16)25-27-23-20(24(28-25)29-8-10-33-11-9-29)5-6-21(26-23)18-4-7-22(32-3)19(12-18)15-31/h4-7,12,16-17,31H,8-11,13-15H2,1-3H3/t16-,17+
InChi Key: RFSMUFRPPYDYRD-CALCHBBNSA-N
PubChem CID: 16736978
MDL Number: MFCD11977741
USAGE: For Research Use Only! Not For Use in Humans. |