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PP2
An inhibitor of the Src family of kinases
Product Overview
Product Name: PP2
Alternate Name/Synonyms: 1-tert-Butyl-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Description: An inhibitor of the Src family of kinases. Inhibits Src and Lck kinase with IC₅₀ values of 36 nM and 31 nM respectively. Also shown to inhibit RIP2( IC₅₀ = 19 nM) and CK1δ (IC₅₀ = 41 nM).
Peptide Sequence: N/A
Appearance: Cream solid
Formulation: N/A
CAS Number: 172889-27-9
Molecular Formula: C₁₅H₁₆ClN₅
Molecular Weight: 301.78
Purity: ≥98% by HPLC
Solubility:DMSO (25 mM) and EtOH (10 mM)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: CC(C)(C)N1C2=C(C(=N1)C3=CC=C(C=C3)Cl)C(=NC=N2)N
InChi: InChI=1S/C15H16ClN5/c1-15(2,3)21-14-11(13(17)18-8-19-14)12(20-21)9-4-6-10(16)7-5-9/h4-8H,1-3H3,(H2,17,18,19)
InChi Key: PBBRWFOVCUAONR-UHFFFAOYSA-N
PubChem CID: 4878
MDL Number: MFCD01568210
USAGE: For Research Use Only! Not For Use in Humans. |