|
Nafamostat Mesylate
A broad spectrum serine protease inhibitor
Product Overview
Product Name: Nafamostat Mesylate
Alternate Name/Synonyms: 4-[(Aminoiminomethyl)amino]benzoic acid 6-(aminoiminomethyl)-2-naphthalenyl ester dimethanesulfonate; FUT-175; Futhan
Description: A broad-spectrum, synthetic serine protease inhibitor and an inhibitor of the classical and alternative ways of complement activation. Displays selectivity for human tryptase when used at relatively low concentrations. Reduces eosinophil infiltration, mast cell activation and airway responsiveness in a murine model of asthma.
Peptide Sequence: N/A
Appearance: Off-white solid
Formulation: N/A
CAS Number: 82956-11-4
Molecular Formula: C₁₉H₁₇N₅O₂.2CH₄O₃S
Molecular Weight: 539.59
Purity: ≥97% by HPLC
Solubility:DMSO (100 mM) and H₂O (100 mM)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and moisture
SMILES: CS(=O)(=O)O.CS(=O)(=O)O.C1=CC(=CC=C1C(=O)OC2=CC3=C(C=C2)C=C(C=C3)C(=N)N)N=C(N)N
InChi: InChI=1S/C19H17N5O2.2CH4O3S/c20-17(21)14-2-1-13-10-16(8-5-12(13)9-14)26-18(25)11-3-6-15(7-4-11)24-19(22)23;2*1-5(2,3)4/h1-10H,(H3,20,21)(H4,22,23,24);2*1H3,(H,2,3,4)
InChi Key: SRXKIZXIRHMPFW-UHFFFAOYSA-N
PubChem CID: 5311180
MDL Number: MFCD00941430
USAGE: For Research Use Only! Not For Use in Humans. |