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Irinotecan Hydrochloride
A DNA topoisomerase I inhibitor
Product Overview
Product Name: Irinotecan Hydrochloride
Alternate Name/Synonyms: S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo1H-pyrano[3’,4’:6,7]-indolizino[1,2-b]quinolin-9-yl-[1,4’bipiperidine]-1’-carboxylate, Hydrochloride
Description: An anticancer agent. This is a prodrug that is converted by tissue carboxylesterase to 7-ethyl-10-hydroxycamptothecin (SN-38), a potent inhibitor of DNA topoisomerase I.
Peptide Sequence: N/A
Appearance: Yellow solid
Formulation: N/A
CAS Number: 100286-90-6
Molecular Formula: C₃₃H₃₈N₄O₆. HCl
Molecular Weight: 623.14
Purity: ≥98% by HPLC
Solubility:DMSO (50 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and moisture
SMILES: CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7.Cl
InChi: InChI=1S/C33H38N4O6.ClH/c1-3-22-23-16-21(43-32(40)36-14-10-20(11-15-36)35-12-6-5-7-13-35)8-9-27(23)34-29-24(22)18-37-28(29)17-26-25(30(37)38)19-42-31(39)33(26,41)4-2;/h8-9,16-17,20,41H,3-7,10-15,18-19H2,1-2H3;1H/t33-;/m0./s1
InChi Key: GURKHSYORGJETM-WAQYZQTGSA-N
PubChem CID: 74990
MDL Number: MFCD01862255
USAGE: For Research Use Only! Not For Use in Humans. |