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Butyrolactone I
Product Overview
Product Name: Butyrolactone I
Alternate Name/Synonyms: BLI, BL-I
Description: Cell permeable. A potent and selective inhibitor of the cyclin-dependent kinases CDK1/cyclin B, CDK2 and CDK5. Inhibits cell cycle progression at the G1/S and G2/M transitions. BLI is an important tool for probing the cellular roles of CDKs. It blocks Fas-induced apoptosis and displays antitumor activity.
Peptide Sequence: N/A
Appearance: White solid
Formulation: N/A
CAS Number: 87414-49-1
Molecular Formula: C₂₄H₂₄O₇
Molecular Weight: 424.44
Purity: ≥99% by HPLC
Solubility:DMSO (10 mg/ml) and Ethanol (25 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: CC(=CCC1=C(C=CC(=C1)COC(=O)C2(C(=C(C(=O)O2)O)C3=CC=C(C=C3)O)C)O)C
InChi: InChI=1S/C24H24O7/c1-14(2)4-6-17-12-15(5-11-19(17)26)13-30-23(29)24(3)20(21(27)22(28)31-24)16-7-9-18(25)10-8-16/h4-5,7-12,25-27H,6,13H2,1-3H3/t24-/m1/s1
InChi Key: FPVUCBMBMUHRDX-XMMPIXPASA-N
PubChem CID: 3035414
MDL Number: MFCD03453074
USAGE: For Research Use Only! Not For Use in Humans. |