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AICAR
Product Overview
Product Name: AICAR
Alternate Name/Synonyms: 5-Aminoimidazole-4-carboxamide 1-β-D-ribofuranoside; AICA-Riboside; NSC 105823
Description: A cell- permeable activator of AMP-activated protein kinase (AMPK), a metabolic sensor involved in both cellular and whole body energy homeostasis. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle. AICAR is able to activate the molecular circuitry of pluripotency in mESC and to induce the expression of several key regulators of pluripotency in somatic cells.
Peptide Sequence: N/A
Appearance: Tan powder
Formulation: N/A
CAS Number: 2627-69-2
Molecular Formula: C₉H₁₄N₄O₅
Molecular Weight: 258.23
Purity: ≥98% by HPLC
Solubility:H₂O
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and moisture
SMILES: C1=NC(=C(N1C2C(C(C(O2)CO)O)O)N)C(=O)N
InChi: InChI=1S/C9H14N4O5/c10-7-4(8(11)17)12-2-13(7)9-6(16)5(15)3(1-14)18-9/h2-3,5-6,9,14-16H,1,10H2,(H2,11,17)/t3-,5-,6-,9-/m1/s1
InChi Key: RTRQQBHATOEIAF-UUOKFMHZSA-N
PubChem CID: 17513
MDL Number: MFCD00869751
USAGE: For Research Use Only! Not For Use in Humans. |