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ATM Kinase Inhibitor, KU-55933
Product Overview
Product Name: ATM Kinase Inhibitor, KU-55933
Alternate Name/Synonyms: 2-Morpholin-4-yl-6-thianthren-1-yl-pyran-4-one; KU-55933
Description: A potent, selective and ATP-competitive inhibitor of ATM Kinase (Ki = 2.2 nM; IC₅₀ = 13 nM). Inhibits DNA-PK, mTOR, PI 3-K, PI 4-K, and ATR at much higher concentrations (IC₅₀ = 2500, 9300, 16600, >100000 and >100000 nM, respectively).
Peptide Sequence: N/A
Appearance: White solid
Formulation: N/A
CAS Number: 587871-26-9
Molecular Formula: C₂₁H₁₇NO₃S₂
Molecular Weight: 395.49
Purity: ≥97% by HPLC
Solubility:DMSO (100 mM) and Ethanol (50 mM)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: C1COCCN1C2=CC(=O)C=C(O2)C3=C4C(=CC=C3)SC5=CC=CC=C5S4
InChi: InChI=1S/C21H17NO3S2/c23-14-12-16(25-20(13-14)22-8-10-24-11-9-22)15-4-3-7-19-21(15)27-18-6-2-1-5-17(18)26-19/h1-7,12-13H,8-11H2
InChi Key: XRKYMMUGXMWDAO-UHFFFAOYSA-N
PubChem CID: 5278396
MDL Number: MFCD08276985
USAGE: For Research Use Only! Not For Use in Humans. |