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RG 108
Product Overview
Product Name: RG 108
Alternate Name/Synonyms: N-Phthalyl-L-tryptophan
Description: A DNA methyltransferase (DNMT) inhibitor. RG108 causes demethylation and reactivation of tumor suppressor genes, but it does not affect the methylation of centromeric satellite sequences. In combination with BIX 01294 (Cat. No. 1678-5), RG 108 enhances reprogramming.
Peptide Sequence: N/A
Appearance: Beige to yelllow solid
Formulation: N/A
CAS Number: 48208-26-0
Molecular Formula: C₁₉H₁₄N₂O₄
Molecular Weight: 334.33
Purity: ≥98% by HPLC
Solubility:DMSO (10 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and moisture
SMILES: C1=CC=C2C(=C1)C(=O)N(C2=O)C(CC3=CNC4=CC=CC=C43)C(=O)O
InChi: InChI=1S/C19H14N2O4/c22-17-13-6-1-2-7-14(13)18(23)21(17)16(19(24)25)9-11-10-20-15-8-4-3-5-12(11)15/h1-8,10,16,20H,9H2,(H,24,25)/t16-/m0/s1
InChi Key: HPTXLHAHLXOAKV-INIZCTEOSA-N
PubChem CID: 702558
MDL Number: N/A
USAGE: For Research Use Only! Not For Use in Humans. |