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BIX 01294
Product Overview
Product Name: BIX 01294
Alternate Name/Synonyms: 2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine
Description: Selectively impairs the G9a histone lysine methyltransferase (HMTase) and the generation of H3K9me2 in vitro. BIX-01294 enables neural progenitor cells (NPCs) to be reprogrammed in the absence of exogenous Oct4.
Peptide Sequence: N/A
Appearance: Off-white solid
Formulation: N/A
CAS Number: 935693-62-2
Molecular Formula: C₂₈H₃₈N₆O₂
Molecular Weight: 490.65
Purity: ≥95% by HPLC
Solubility:DMSO (10 mg/ml) or Ethanol (10 mg/ml)
Storage Temp.: +4C
Shipping Conditions: RT
Handling: Protect from air and moisture
SMILES: CN1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCN(CC4)CC5=CC=CC=C5)OC)OC
InChi: InChI=1S/C28H38N6O2/c1-32-12-7-13-34(17-16-32)28-30-24-19-26(36-3)25(35-2)18-23(24)27(31-28)29-22-10-14-33(15-11-22)20-21-8-5-4-6-9-21/h4-6,8-9,18-19,22H,7,10-17,20H2,1-3H3,(H,29,30,31)
InChi Key: OSXFATOLZGZLSK-UHFFFAOYSA-N
PubChem CID: 25150857
MDL Number: MFCD14560563
USAGE: For Research Use Only! Not For Use in Humans. |