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Compound 401
Product Overview
Product Name: Compound 401
Alternate Name/Synonyms: 2-(4-Morpholinyl)-4H-pyrimido[2,1-a]isoquinolin-4-one
Description: Cell-permeable. A reversible and selective inhibitor of DNA-dependent protein kinase (DNA-PK) (IC₅₀ = 0.28 µM) that also targets mTOR (IC₅₀ = 5. 3µM), but not PI 3-K in vitro. Induces apoptosis in vitro.
Peptide Sequence: N/A
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 168425-64-7
Molecular Formula: C₁₆H₁₅N₃O₂
Molecular Weight: 281.31
Purity: ≥97% by HPLC
Solubility:DMSO (10 mM) or EtOH (5 mM)
Storage Temp.: +4°C
Shipping Conditions: RT
Handling: Protect from air and light
SMILES: C1COCCN1C2=CC(=O)N3C=CC4=CC=CC=C4C3=N2
InChi: InChI=1S/C16H15N3O2/c20-15-11-14(18-7-9-21-10-8-18)17-16-13-4-2-1-3-12(13)5-6-19(15)16/h1-6,11H,7-10H2
InChi Key: BVRDQVRQVGRNHG-UHFFFAOYSA-N
PubChem CID: 10039361
MDL Number: MFCD10568147
USAGE: For Research Use Only! Not For Use in Humans. |