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GSK-3β Inhibitor, TWS119
Product Overview
Product Name: GSK-3β Inhibitor, TWS119
Alternate Name/Synonyms: 3-[[6-(3-Aminophenyl)-1H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-phenol
Description: A potent inhibitor of GSK-3β (Glycogen synthase kinase-3β) (IC₅₀ = 30 nM). At 400 nM, TWS119 induces neurogenesis in murine embryonic stem cells making it a useful tool to regulate stem cell self-renewal and differentiation.
Peptide Sequence: N/A
Appearance: Slightly pink solid
Formulation: N/A
CAS Number: 601514-19-6
Molecular Formula: C₁₈H₁₄N₄O₂
Molecular Weight: 318.33
Purity: ≥95% by HPLC
Solubility:DMSO (20 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: C1=CC(=CC(=C1)N)C2=CC3=C(N2)N=CN=C3OC4=CC=CC(=C4)O
InChi: InChI=1S/C18H14N4O2/c19-12-4-1-3-11(7-12)16-9-15-17(22-16)20-10-21-18(15)24-14-6-2-5-13(23)8-14/h1-10,23H,19H2,(H,20,21,22)
InChi Key: VPVLEBIVXZSOMQ-UHFFFAOYSA-N
PubChem CID: 9549289
MDL Number: MFCD09037535
USAGE: For Research Use Only! Not For Use in Humans. |