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Y-27632, Dihydrocholride
Product Overview
Product Name: Y-27632, dihydrochloride
Alternate Name/Synonyms: trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecar boxamide dihydrochloride
Description: Selective inhibitor of the Rho-associated protein kinase p160ROCK. Ki values are 0.14, 26, 25 and >250 µM for p160ROCK, PKC, cAMP-dependent protein kinase and myosin light-chain kinase, respectively. Prevents apoptosis as well as enhance the survival and cloning efficiency of dissociated human embryonic stem cells (hES) without affecting their pluripotency.
Peptide Sequence: N/A
Appearance: White soild
Formulation: N/A
CAS Number: 146986-50-7
Molecular Formula: C₁₄H₂₁N₃O.2HCl
Molecular Weight: 320.26
Purity: ≥99% by HPLC
Solubility:H₂O (100 mM) or PBS (100 mM)
Storage Temp.: -20°C
Shipping Conditions: RT
Handling: Protect from air and moisture
SMILES: CC(C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl
InChi: InChI=1S/C14H21N3O.2ClH/c1-10(15)11-2-4-12(5-3-11)14(18)17-13-6-8-16-9-7-13;;/h6-12H,2-5,15H2,1H3,(H,16,17,18);2*1H/t10-,11?,12?;;/m1../s1
InChi Key: IDDDVXIUIXWAGJ-DDSAHXNVSA-N
PubChem CID: 9901617
MDL Number: MFCD03490488
USAGE: For Research Use Only! Not For Use in Humans. |