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MS-275 (Entinostat, SNDX-275)
Product Overview
Product Name: MS-275 (Entinostat, SNDX-275)
Alternate Name/Synonyms: Entinostat, SNDX-275
Description: Preferentially inhibits HDAC1 (IC₅₀ = 300 nM) over HDAC3 (IC₅₀ = 8 µM). Has no inhibitory activity towards HDAC8 (IC₅₀>100 µM).
Peptide Sequence: N/A
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 209783-80-2
Molecular Formula: C₂₁H₂₀N₄O₃
Molecular Weight: 376.41
Purity: ≥99% by HPLC
Solubility:DMSO (38 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: RT
Handling: Protect from light and moisture
SMILES: C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC(=O)OCC3=CN=CC=C3
InChi: InChI=1S/C21H20N4O3/c22-18-5-1-2-6-19(18)25-20(26)17-9-7-15(8-10-17)13-24-21(27)28-14-16-4-3-11-23-12-16/h1-12H,13-14,22H2,(H,24,27)(H,25,26)
InChi Key: INVTYAOGFAGBOE-UHFFFAOYSA-N
PubChem CID: 4261
MDL Number: MFCD08272435
USAGE: For Research Use Only! Not For Use in Humans. |