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PD184352
Product Overview
Product Name: PD184352
Alternate Name/Synonyms: CI-1040
Description: A highly potent ATP-noncompetitive MEK inhibitor. It inhibits MEK with an in vitro IC₅₀ of 1-1.3 nM. It does not inhibit other kinases. Highly recommended tool to inhibit MKK1 or MKK1 plus MKK5.
Peptide Sequence: N/A
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 212631-79-3
Molecular Formula: C₁₇H₁₄ClF₂IN₂O₂
Molecular Weight: 478.67
Purity: ≥99% by HPLC
Solubility:DMSO (600 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from light and moisture
SMILES: C1CC1CONC(=O)C2=C(C(=C(C=C2)F)F)NC3=C(C=C(C=C3)I)Cl
InChi: InChI=1S/C17H14ClF2IN2O2/c18-12-7-10(21)3-6-14(12)22-16-11(4-5-13(19)15(16)20)17(24)23-25-8-9-1-2-9/h3-7,9,22H,1-2,8H2,(H,23,24)
InChi Key: GFMMXOIFOQCCGU-UHFFFAOYSA-N
PubChem CID: 6918454
MDL Number: MFCD02683961
USAGE: For Research Use Only! Not For Use in Humans. |