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Axitinib (AG-013736)
Product Overview
Product Name: Axitinib (AG-013736)
Alternate Name/Synonyms: AG-013736
Description: Axitinib (also known as AG-013736) is a small molecule tyrosine kinase inhibitor. It inhibits multiple targets, including VEGFR-1, VEGFR-2, VEGFR-3, PDGFR, and cKIT (CD117). It has been shown to significantly inhibit growth of breast cancer in xenograft models and renal cell carcinoma (RCC) and several other tumor types.
Peptide Sequence: N/A
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 319460-85-0
Molecular Formula: C₂₂H₁₈N₄OS
Molecular Weight: 386.47
Purity: ≥99% by HPLC
Solubility:DMSO (10 mM)
Storage Temp.: -20°C
Shipping Conditions: RT
Handling: Protect from light and moisture
SMILES: CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3)C=CC4=CC=CC=N4
InChi: InChI=1S/C22H18N4OS/c1-23-22(27)18-7-2-3-8-21(18)28-16-10-11-17-19(25-26-20(17)14-16)12-9-15-6-4-5-13-24-15/h2-14H,1H3,(H,23,27)(H,25,26)/b12-9+
InChi Key: RITAVMQDGBJQJZ-FMIVXFBMSA-N
PubChem CID: 6450551
MDL Number: MFCD09837898
USAGE: For Research Use Only! Not For Use in Humans. |