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Cerulenin
Product Overview
Product Name: Cerulenin
Alternate Name/Synonyms: 2,3-Epoxy-4-oxo-7,10-dodecadienamide
Description: Antibiotic. Fatty acid synthase (FAS) inhibitor, reported to bind in equimolar ratio to β-keto-acyl-ACP synthase, thus inhibiting protein acylation. Produces metabolic effects similar to effects of leptin, but through mechanisms that are independent of, or downstream from, both leptin and melanocortin receptors. Apoptosis inducer. Inhibitor of bacterial fatty acid synthesis (inhibits FabH, FabB and FabF condensation enzymes).
Peptide Sequence: N/A
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 17397-89-6
Molecular Formula: C₁₂H₁₇NO₃
Molecular Weight: 223.3
Purity: ≥98%
Solubility:DMSO (20 mg/ml) or EtOH (20 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from light and air
SMILES: CC=CCC=CCCC(=O)C1C(O1)C(=O)N
InChi: InChI=1S/C12H17NO3/c1-2-3-4-5-6-7-8-9(14)10-11(16-10)12(13)15/h2-3,5-6,10-11H,4,7-8H2,1H3,(H2,13,15)
InChi Key: GVEZIHKRYBHEFX-UHFFFAOYSA-N
PubChem CID: 272023
MDL Number: MFCD00077686
USAGE: For Research Use Only! Not For Use in Humans. |