|
JWH 072
Cayman Chemical Item Number 9001201
(CAS 209414-06-2)
Description
JWH 072 is a synthetic cannabinoid (CB) that displays a higher affinity for the peripheral CB2 receptor (Ki = 170 nM) than the central CB1 receptor (Ki = 1,050 nM).1↗,2↗ The physiological and toxicological properties of this compound are not known. This product is intended for research and forensic purposes.
1 Aung, M.M., Griffin, G., Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding. Drug Alcohol Depend 60 133-140 (2000).
2 Huffman, J.W., Zengin, G., Wu, M., et al. Structure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB1 and CB2 receptors: steric and electronic effects of naphthoyl substituents. New highly selective CB2 receptor agonists. Bioorg Med Chem 13 89-112 (2005).
Formal Name 1-naphthalenyl(1-propyl-1H-indol-3-yl)-methanone
CAS Number 209414-06-2
Molecular Formula C22H19NO
Formula Weight 313.4
Formulation A crystalline solid
Purity ≥98%
λmax 219, 247, 314 nm
Stability 2 years
Storage -20°C
Shipping Wel ice in continental US; may vary elsewhere
SMILES Copy O=C(C1=CN(CCC)C2=C1C=CC=C2)C3=C4C(C=CC=C4)=CC=C3
InCHI Code Copy 1S/C22H19NO/c1-2-14-23-15-20(18-11-5-6-13-21(18)23)22(24)19-12-7-9-16-8-3-4-10-17(16)19/h3-13,15H,2,14H2,1H3
InCHI Key Copy IVLWWVXVWRIXSS-UHFFFAOYSA-N |