Chemokine-Like Receptor 1 Polyclonal Antibody

产品编号：	10325-1 查看说明书
产品名称：	Chemokine-Like Receptor 1 Polyclonal Antibody .0 订购此产品
供应商：	Cayman
规格：	1 ea
目录价：	3626
库存状态：	3周
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Chemokine-Like Receptor 1 Polyclonal Antibody Cayman Chemical Item Number 10325 Description Antigen: human CMKLR1 amino acids 358-371 (NERTSMNERETGML) · Host: rabbit · Application(s): FC, ICC, and WB · Chemokine-Like Receptor 1 (CMKLR1) is a G protein-coupled receptor relevant to the cellular chemotaxis of dendritic cells and macrophages.1↗ This receptor is also expressed in brain, liver, lung, and kidney tissues.1↗,2↗ Chemerin, or TIG2, has been identified as the natural ligand for this receptor.3↗ Resolvin E1 has also been identified as a ligand for CMKLR1; acting to dampen cellular responses to inflammation.1↗,4↗,5↗ Chemerin is an 18 kDa protein that plays a role in immunity, inflammation, chemotaxis, and has been identified as an adipokine.6↗,7↗,2↗ Human CMKLR1 shares 80% sequence homology with its mouse ortholog.3↗ The human receptor exists in two isoforms, differing only by two amino acids due to a premature stop codon. Isoform one has 363 amino acids and an expected molecular weight of 42.3 kDa. Cayman’s CMKLR1 polyclonal antibody recognizes the C-terminal region of the protein and cell permeabilization is recommended prior to whole cell staining. Synonyms CMKLR1,DEZ,Resolvin E1 Receptor,GPCR ChemR23 Formulation Peptide affinity-purified IgG lyophilized from TBS, pH 7.4 Stability 2 years Storage -20°C Shipping Room temperature in continental US; may vary elsewhere Specificity Human CMKLR1,Monkey CMKLR1,Mouse CMKLR1
保存条件：	-20°C
说明书地址：	点击查看详细

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