GPR55 Polyclonal Antibody

产品编号：	10224-1 查看说明书
产品名称：	GPR55 Polyclonal Antibody .0 订购此产品
供应商：	Cayman
规格：	1 ea
目录价：	3626
库存状态：	3周
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GPR55 Polyclonal Antibody Cayman Chemical Item Number 10224 Description Antigen: human GPR55 amino acids 207-219 (ILLGRRDHTQDWV) · Host: rabbit · Application(s): FC, ICC, and WB · GPR55 is a G protein-coupled receptor that has been identified as a novel cannabinoid receptor, although its exact role is still controversial.1↗,2↗ Previously central cannabinoid (CB1) and peripheral cannabinoid (CB2), two widely characterized receptors have been shown to bind THC the active component of cannabis and other endocannabinoids. Mounting evidence suggests that additional receptors play a role in cannabinoid-related signal transduction and GPR55 has been identified as one of them.3↗ This receptor is widely expressed in the brain, specifically found in large dorsal root ganglion neurons.4↗ Along with binding THC, it also shows high affinity to anandamide, methanandamide, JWH015, and many other cannabinoid ligands.5↗,6↗ The human protein shows 75% and 78% overall sequence homology with the rat and mouse proteins, respectively.1↗ GPR55 is composed of 319 amino acids and has an expected molecular weight of 37 kDa. Post-translational modifications such as glycosylation may retard receptor electrophoretic migration and thereby protein signal may be detected above 37 kDa. Synonyms G Protein-Coupled Receptor 55 Formulation Peptide affinity-purified IgG lyophilized from TBS, pH 7.4 Stability 2 years Storage -20°C Shipping Room temperature in continental US; may vary elsewhere Specificity Human GPR55,Bovine GPR55,Mouse (Neuro-2a cells) GPR55
保存条件：	-20°C
说明书地址：	点击查看详细

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