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Tolvaptan
Description
A potent human vasopressin V2-receptor antagonist. It increases serum sodium concentration in patients with euvolemic or hypervolemic hyponatremia.
Specifications
Cas No. 150683-30-0
Product ID T5847
Product Name Tolvaptan
Chemical Name N-(4-{[(5R)-7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl}-3-methylphenyl)-2-methylbenzamide
Synonym OPC-41061
Formula Wt. 448.94
References Yamamura Y, Nakamura S, Itoh S, et al. J. Pharmacol Exp Ther. 287:860-7 (1998). Schrier RW, Gross P, Gheorghiade M, et. al N Engl J Med 355:2099-112 (2006).
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