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Tolfenamic acid
Description
Non steroidal anti-inflammatory agent. Found to inhibit COX-2 isoenzymes in dogs. Analgesic property is due to activation of Ca(2+0-activated K(+) channels.
See more information about other Cox 2 Inhibitors
Specifications
Cas No. 13710-19-5
Product ID T5846
Product Name Tolfenamic acid
Chemical Name 2-[(3-Chloro-2-methylphenyl)amino]benzoic acid
Synonym Clotam; Tolfedine; Tolfine
Formula Wt. 261.7
Melting Point 207oC-207.5oC
Purity ≥98%
Solubility Slightly soluble in water; freely sol in buffers with pH >8.2
Store Temp Ambient
References Kay-mugford P, Benn SJ, et al. Am J Vet Res 61:802-810 (2000) Li L, et al. Eur j Pharmacol .383:169-176 (1999)
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