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Toremifene Base
Description
A chlorinated tamoxifen analogue. It competes with estradiol for estrogen receptors and has growth inhibitory effects on MCF-7 breast cancer cells. It causes growth inhibition of estrogen-sensitive breast cancer cells by inducing some cells to undergo apo
Specifications
Cas No. 89778-26-7
Product ID T5769
Product Name Toremifene Base
Chemical Name 2-[4-[(1Z)-4-Chloro-1,2-diphenyl-1-butenyl]phenoxy]-N,N-dimethylethanamine
Synonym Toremifene
Formula Wt. 405.96
Melting Point 108oC-110oC
Purity ≥98%
Store Temp Ambient
References Maenpaa JU, Ala-Fossi SL. Drugs Aging. 11:261-70 (1997). Warri AM, Huovinen RL, Laine AM, Martikanein PM, Harkonen PL. J Natl Cancer Inst. 85:1412-8 (1993).
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