Rosiglitazone Maleate Description A thiazolidinedione antidiabetic agent. It is a potent insulin sensitizing agent and a peroxisome proliferator-activated receptor-y (PPAR-y) agonist. It was found to have hepatoxicity. Specifications Cas No. 155141-29-0 Product ID R5772 Product Name Rosiglitazone Maleate Chemical Name 5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione Synonym BRL-49653c; Avandia Formula Wt. 473.51 Melting Point 122 Purity ≥98% Solubility Readily soluble in ethanol and in buffered aqueous solutions with a pH of 2.3. Store Temp Ambient Ship Temp Ambient References McMorran M. Vu D. CMAJ. 165:82-3, 86-7 (2001). Parks DJ. Tomkinson NC. Villeneuve MS. et al. Bioorg Med Chem Lett. 8:3657-8 (1998). Knock GA. Mishra SK. Aaronson PI. Eur J Pharmacol. 368:103-9 (1999).