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Nigericin Sodium
Description
A potassium ionophore, found to induce cell death and promote the maturation and release of IL-1beta in lipopolysaccharide primed monocytes and macrophages. It also enhances rapamycin action.
Specifications
Cas No. 28643-80-3
Product ID N3225
Product Name Nigericin Sodium
Chemical Name Antibiotic K 178 Sodium salt
Synonym Azalomycin M; Helixin C; Polyetherin A.
Formula Wt. 747
Melting Point 245oC-255oC
Purity ≥98%
Solubility Soluble in chloroform. Practically insoluble in water.
Store Temp +4oC
References Fang A, Wong GK, Demain AL. J Antibiot (Tokyo). 53:158-62 (2000). Hentze H, Lin XY, Choi MS et al. Cell Death Differ. 10:956-68 (2003).
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