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Ivermectin
Description
An anthelmintic found to be a competitive inhibitor of specific [3H]-GABA binding site in nematodes. It activates the glycine receptor chloride channel.
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Specifications
Cas No. 70288-86-7
Product ID I8618
Product Name Ivermectin
Chemical Name 22,23-Dihydroabamectin
Synonym 22,23-Dihydroavermectin B1; MK-933; Heartgard 30; Mectizan; Stromectol; Zimecterin
Formula Wt. 875.09
Melting Point 155
Purity ≥95%
Solubility Soluble in methyl ethyl ketone, propylene glycol, and polyethylene glycol. Insoluble in water.
Store Temp +4oC
References Ros-Moreno RM, Moreno-Guzman MJ, Jimenez-Gonzalez A et al. Parasitol Res. 85:320-3 (1999). Shan Q, Haddrill JL, Lynch JW. J Biol Chem. 276:12556-64 (2001).
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