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Irsogladine Maleate
Description
An anti-gastric ulcer agent that facilitates gap-junctional intercellular communication through M1 muscarininc acetylcholine receptor binding. It is a potent inhibitor of angiogenesis and protects MNNG-induced gastric carcinogenesis in rats.
Specifications
Cas No. 84504-69-8
Product ID I7074
Product Name Irsogladine Maleate
Chemical Name 6-(2,5-Dichlorophenyl)-1,3,5-triazine-2,4-diamine maleate
Synonym MN-1695; Gaslon
Formula Wt. 372.17
Melting Point 289
Purity ≥98%
Solubility Soluble in DMSO.
Store Temp Ambient
References Ueda F, Ban K, Ishima T. J Pharmacol Exp Ther. 274:815-9 (1995). Sato Y, Morimoto A, Kiue A et al. FEBS Lett. 322:155-8 (1993). Ren CJ, Ueda F, Roses DF et al. J Surg Res. 77:126-31 (1998). Sugie S, Okamoto K, Watanabe T et al. Toxicology. 166:53-61 (200
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