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Esculetin
Description
A lipoxygenase inhibitor. Also a potent chemopreventive agent capable of reducing oxidative stress in liver, inhibiting carcinogen DNA binding in human bronchial epithelial cells and inducing reduced glutathione in buffalo rat liver cells.
Specifications
Cas No. 305-01-1
Product ID E7309
Product Name Esculetin
Chemical Name 6,7-Dihydroxy-2H-1-benzopyran-2-one
Synonym 6,7-Dihydroxycoumarin; Cichorigenin
Formula Wt. 178.14
Melting Point 268oC -270oC
Purity ≥98%
Solubility Soluble in dil alkalies, hot alcohol or glacial acetic acid. Insoluble in ether or boiling water.
Store Temp Ambient
References Matsunaga K, Yoshimi N, Yamada Y, Shimizu M, Kawataba K, Ozawa Y, Hara A, Mori H, Jpn. J. Cancer Res. 89:496-501 (1998). Lin WL, Wang CJ, Tsai YY, Liu CL, Hwang JM, Tseng TH. Arch. Toxicol. 74:467-72 (2000). Sharma S, Stutzman JD, Kelloff GJ, Steele VE. C
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