Endothelin-1, human Description It is produced by endothelial cells, neurons and astrocytes in the central nervous system, hepatocytes and Sertoli cells. It has an important role in the paracrine regulation of cardiovascular functions in humans. Specifications Product ID E5219 Product Name Endothelin-1, human Formula Wt. 2491.95 Store Temp +4oC References Yanagisawa, M. et al. Nature. 332:411 (1988).