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Mechlorethamine HCl
Description
A chemotherapeutic agent showing antitumor activity attributed to its ability to cross-link the twin strands of DNA. A one-hour exposure caused a transient late S/G2 cell cycle arrest in both the HL-60 cell line and the Colo 320HSR human colon cancer cell line.
Specifications
Cas No. 55-86-7
Product ID C2942
Product Name Mechlorethamine HCl
Chemical Name 2-Chloro-N-(2-chloroethyl)-N-methylethanamine, N-Methylbis(2-chloroethyl)amine hydrochloride
Synonym Nitrogen mustard, Bis(2-Chloroethyl)methylamine
Formula Wt. 192.51
Melting Point 108-111
Store Temp +4°C
Ship Temp Ambient
References Xie J, Shults K, Flye L et al. J Cell Biochem. 95:339-351 (2005). Balcome S, Park S, Quirk Dorr DR et al. Chem Res Toxicol. 17:950-962 (2004).
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