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Bisacodyl
Description
A diphenolic laxative. It is suggested that intestinal inhibition of (Na+K) ATPhase activity, increase of mucosal PGE2 content, and possibly also stimulation of adenyl cyclase activity might contribute to the net water accumulation induced by bisacodyl.
Specifications
Cas No. 603-50-9
Product ID B3374
Product Name Bisacodyl
Chemical Name 4,4'-(2-Pyridylmethylene)-bisphenol diacetate
Synonym Bicol; Broxalax; Contalax; DAMP; Dulrolax; Endokolat; Laxadin; Laxorex; Perilax; Telemin; Ulcolax
Formula Wt. 361.39
Melting Point 138oC
Purity ≥98%
Solubility Soluble in acids, acetone, propylene glycol and other organic solvents. Practically insoluble in water and alkaline solutions.
Store Temp +4oC
References Farack UM, Nell G. Digestion. 30:191-4 (1984). Rachmilewitz D, Karmeli F, Okon E. Dig Dis Sci. 25:602-8 (1980).
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