|
Baicalin
Description
Baicalin is one of the flavonoids found in the radix of Scutellaria baicalensis that has antioxidant activity. It scavenges hydroxyl radical, DPPH radical and alkyl radical, and protects cells from oxidative damage. Baicalin also exhibits a variety of biological activities. Its antiinflammatory effect was observed by its inhibition against carrageenan-induced rat paw edema. It has anti-HIV activity. The replication of HIV-1 was inhibited in a dose-dependent manner. One of the mechanisms of inhibition is likely the induction of apoptosis. Baicalin was found also to inhibit colon aberrant crypts formation induced by azoxymethane and suppressed the growth and metastasis of malignant melanoma in ret-transgenic mice.
Specifications
Cas No. 21967-41-9
Product ID B0133
Product Name Baicalin
Synonym 7-D-Glucuronic acid-5,6-dihydroxyflavone
Formula Wt. 446.36
Melting Point 202-205oC (lit.)
Purity 95%
Solubility Soluble in DMSO or ethanol.
Store Temp -20oC
Ship Temp Ambient
References Gao, Z., Huang, K., Yang, X., Xu, H. Biiochem. Biophys. Acta. 1472:643-650 (1999). Lin, C.C., Shieh, D.E. Am. J. Chin. Med. 24:31-36 (1996). Kitamura, K., Honda, M., Yoshizaki, H., et al. Antiviral Res. 37:131-140 (1998). Wu, X., Akatsu, H., Okada,
|