|
Aphidicolin
Description
A DNA polymerase inhibitor. Potentiates apoptosis induced by therapeutic nucleosides.
Specifications
Cas No. 38966-21-1
Product ID A6229
Product Name Aphidicolin
Chemical Name (3a,4a,5a,17a)-3,17-Dihydroxy-4-methyl-9,15-cyclo-C,18-dinor-14,15-secoandrostane-4,17-dimethanol
Synonym ICI-69653; NSC-234714
Formula Wt. 338.48
Melting Point 227oC-232oC
Purity ≥98%
Solubility Soluble in DMSO, ethanol.
Store Temp -20oC
References Kuwakado, K., Kubota, M.., Hirota, H., et al. Biochem Pharmacol. 46:1909-16 (1993). Lin, C.K., Nguyen, T.T., Morgan, T.L., et al. Exp. Cell Res. 244:1-13 (1998).
|