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Amrinone
Description
Selective phosphodiesterase III inhibitor. A nonglycoside, noncatecholamine agent with positive inotropic effect. Inhibits cyclic AMP-dependent protein kinase activity by competing with ATP but not cyclic AMP binding sites. I
Specifications
Cas No. 60719-84-8
Product ID A5170
Product Name Amrinone
Chemical Name 5-Amino-(3,4'-bipyridin)-6(1H)-one
Synonym Cartonic; Inocor; Vesistol; Wincoram
Formula Wt. 187.2
Melting Point 294oC-297oC(dec.)
Purity ≥98%
Solubility Insoluble in water. Slightly soluble in hot acetic acid and dimethylformamide. Soluble in dilute inorganic acids.
Store Temp +4oC
Ship Temp Ambient
References Ono S, Ueda S, Sakuma T et al. J Cardiov. Surgery 37:177-81 (1996). Earl CQ, Linden J, Weglicki WB. Life Sciences 39:1901-8 (1986). Kikura M, Kazama T, Ikeda T et al. Platelets 11:446-58 (2000).
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