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Amlodipine
Description
A calcium channel antagonist with potent antioxidant activity. It inhibits doxorubicin-induced myocyte apoptosis by supressing the mitochondrial apoptotic pathway.It has been found to inhibit hyperplasia and hypertrophy
Specifications
Cas No. 88150-42-9
Product ID A5045
Product Name Amlodipine
Chemical Name 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4- dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester
Synonym UK-48340
Formula Wt. 408.88
Melting Point 134oC-136 oC
Purity ≥98%
Solubility Soluble in methanol, choroform and DMSO.
Store Temp Ambient
Ship Temp Ambient
References Yamanka S, Tatsumi T, Shiraishi J et al. J Am Coll Cardiol. 41:870-8 (2003). Shultz PJ, Raij L. Am J Hypertens. 5:912-4 (1992).
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