|
Alsterpaullone
Description
The most active paullone. It is a potent inhibitor of glycogen synthase kinase-3b and cyclin - dependent kinase 5/p25. It has been shown to induce apoptosis and promote loss in clonogenicity in the Jurkate cell line.
Specifications
Cas No. 237430-03-4
Product ID A4577
Product Name Alsterpaullone
Synonym 9-Nitro-7,12-dihydroindolo-[3,2-d][1]benzazepin-6(5)-one
Formula Wt. 293.28
Purity ≥98%
Solubility Soluble in DMSO.
Stability Protect from light.
Store Temp +4oC
References Leost M, Schultz C, Link A et al. European J Biochem. 267:5983-94 (2000). Lahusen T, De Siervi A, Kunick C et al. Molecular Carcinogenesis. 36:183-94 (2003).
|