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B-1080 Bafilomycin A1, >98%
M.W. 622.83
C35H58O9
[88899-55-2]
Storage: Store at or below -20 ºC. Solubility: Soluble in DMSO at 200 mg/mL; may react with methanol or ethanol, so these solvents are not recommended for stock solutions; very poorly soluble in water; maximum solubility in plain water is estimated to be about 5-10 µM; buffers, serum, or other additives may increase or decrease the aqueous solubility. Appearance: Clear film. Disposal: A
Specific, potent inhibitor of vacuolar ATPases. Bowman, E.J., et al. "Bafilomycins: A class of inhibitors of membrane ATPase from microorganisms, animal cells, and plant cells." Proc. Natl. Acad. Sci. USA 85: 7972-7976 (1988).
Sold for laboratory or manufacturing purposes only; not for human, medical, veterinary, food, or household use.
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