AS-1269574

产品编号：	10626-25 查看说明书
产品名称：	AS-1269574 .0 订购此产品
供应商：	Cayman
规格：	25 mg
目录价：	3234
库存状态：	3周
CAS编号：	330981-72-1
应用范围：
种属来源：
相关信息：
AS-1269574 Cayman Chemical Item Number 10626 Description GPR119, a glucose-dependent insulinotropic receptor, is a Gs protein-coupled receptor that is expressed in pancreas β-cells and intestinal L-cells.1↗ Activation of GPR119 by the endogenous ligands lyso-phosphatidylcholine and oleoyl ethanolamide increases intracellular cAMP levels and promotes glucose-stimulated insulin secretion.1↗,2↗ AS-1269574 is an agonist of GPR119 that is effective both in isolated cells and in vivo.3↗ It increases cAMP levels in HEK293 cells transfected with human GPR119 (EC50 = 2.5 μM) and glucose-stimulated insulin secretion in mice (100 mg/kg).3↗ Formal Name 2-[[2-(4-bromophenyl)-6-methyl-4-pyrimidinyl]amino]-ethanol CAS Number 330981-72-1 Molecular Formula C13H14BrN3O Formula Weight 308.2 Formulation A solution in ethanol Purity ≥98% Stability 1 year Storage -20°C Shipping Room temperature in continental US; may vary elsewhere SMILES BrC(C=C1)=CC=C1C2=NC(NCCO)=CC(C)=N2 InCHI Code 1S/C13H14BrN3O/c1-9-8-12(15-6-7-18)17-13(16-9)10-2-4-11(14)5-3-10/h2-5,8,18H,6-7H2,1H3,(H,15,16,17) InCHI Key DUKPGOOUJNUIOI-UHFFFAOYSA-N
保存条件：	-20°C
说明书地址：	点击查看详细

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