BayCysLT2

产品编号：	10532-25 查看说明书
产品名称：	BayCysLT2 .0 订购此产品
供应商：	Cayman
规格：	25 mg
目录价：	11596.2
库存状态：	3周
CAS编号：	712313-33-2
应用范围：
种属来源：
相关信息：
BayCysLT2 Exclusive Cayman Chemical Item Number 10532 Description The cysteinyl leukotrienes LTC4 and LTD4 are potent mediators of asthma and hypersensitivity. They induce bronchoconstriction, increase microvascular permeability, and are vasoconstrictors of coronary arteries. Their biological effects are transduced by a pair of G-protein coupled receptors, CysLT1 and CysLT2.1↗,2↗,3↗ BayCysLT2 is a potent CysLT2 receptor antagonist that inhibits radioligand binding of LTD4 to CysLT2 and CysLT1 receptor cell lines with IC50 values of 35 and >10,000 nM, respectively.4↗ BayCysLT2 concentration-dependently reverses LTC4-stimulated perfusion pressure increase and contractility decrease in isolated Langendorff-perfused guinea pig hearts.4↗ Synonyms CAY10633 Formal Name 3-[[(3-carboxycyclohexyl)amino]carbonyl]-4-[3-[4-(4-phenoxybutoxy)phenyl]propoxy]-benzoic acid CAS Number 712313-33-2 Molecular Formula C34H39NO8 Formula Weight 589.7 Formulation A crystalline solid Purity ≥95% Stability 2 years Storage -20°C Shipping Room temperature in continental US; may vary elsewhere SMILES O=C(NC1CCCC(C(O)=O)C1)C2=CC(C(O)=O)=CC=C2OCCCC(C=C3)=CC=C3OCCCCOC4=CC=CC=C4 InCHI Code 1S/C34H39NO8/c36-32(35-27-10-6-9-25(22-27)33(37)38)30-23-26(34(39)40)15-18-31(30)43-21-7-8-24-13-16-29(17-14-24)42-20-5-4-19-41-28-11-2-1-3-12-28/h1-3,11-18,23,25,27H,4-10,19-22H2,(H,35,36)(H,37,38)(H,39,40) InCHI Key GKPAULTWHHPIHX-UHFFFAOYSA-N
保存条件：	-20°C
说明书地址：	点击查看详细

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