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您现在的位置:产品中心 >>
分子生化试剂 >> 生化试剂 |
BM 567
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产品编号: |
10155-1
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产品名称:
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BM 567 .0 订购此产品 |
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供应商:
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Cayman |
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规格: |
1 mg |
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目录价: |
739.2 |
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库存状态: |
3周 |
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CAS编号:
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284464-77-3 |
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应用范围: |
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种属来源: |
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相关信息: |
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BM 567
Cayman Chemical Item Number 10155
Description
Thromboxane A2 (TXA2) is a potent thrombogenic and vasoconstrictor eicosanoid, produced in large quantities by activated platelets. TXA2 has been implicated as a causal factor in the onset of stroke and myocardial infarction. BM 567 is a dual acting antithrombogenic agent, acting as an inhibitor of TXA2 synthase and as an antagonist of the TP receptor, the G protein-coupled receptor mediating TXA2 activity in platelets and vascular smooth muscle. BM 567 antagonizes the vascular smooth muscle TP receptor with an IC50 value of 1.1 nM. It inhibits platelet TX synthase with an IC50 value of 12 nM.1↗
Formal Name 2-(cyclohexylamino)-5-nitro-N-[(pentylamino)carbonyl]-benzenesulfonamide
CAS Number 284464-77-3
Molecular Formula C18H28N4O5S
Formula Weight 412.5
Formulation A crystalline solid
Purity >98%
λmax 212, 365 nm
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES CCCCCNC(=O)NS(=O)(=O)c1cc(ccc1NC1CCCCC1)[N](=O)O
InCHI Code 1S/C18H28N4O5S/c1-2-3-7-12-19-18(23)21-28(26,27)17-13-15(22(24)25)10-11-16(17)20-14-8-5-4-6-9-14/h10-11,13-14,20H,2-9,12H2,1H3,(H2,19,21,23)
InCHI Key WNIPBGJWMANRGA-UHFFFAOYSA-N |
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保存条件: |
-20°C |
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说明书地址: |
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