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BM 567

产品编号: 10155-1     查看说明书
产品名称: BM 567  .0   订购此产品 
供应商: Cayman
规格: 1 mg
目录价: 739.2
库存状态: 3周
CAS编号: 284464-77-3
应用范围:
种属来源:
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BM 567 Cayman Chemical Item Number 10155 Description Thromboxane A2 (TXA2) is a potent thrombogenic and vasoconstrictor eicosanoid, produced in large quantities by activated platelets. TXA2 has been implicated as a causal factor in the onset of stroke and myocardial infarction. BM 567 is a dual acting antithrombogenic agent, acting as an inhibitor of TXA2 synthase and as an antagonist of the TP receptor, the G protein-coupled receptor mediating TXA2 activity in platelets and vascular smooth muscle. BM 567 antagonizes the vascular smooth muscle TP receptor with an IC50 value of 1.1 nM. It inhibits platelet TX synthase with an IC50 value of 12 nM.1↗ Formal Name 2-​(cyclohexylamino)-​5-​nitro-​N-​[(pentylamino)carbonyl]-​benzenesulfonamide CAS Number 284464-77-3 Molecular Formula C18H28N4O5S Formula Weight 412.5 Formulation A crystalline solid Purity >98% λmax 212, 365 nm Stability 2 years Storage -20°C Shipping Room temperature in continental US; may vary elsewhere SMILES CCCCCNC(=O)​NS(=O)​(=O)​c1cc(ccc1NC1CCCCC1)​[N]​(=O)​O InCHI Code ​1S/C18H28N4O5S/c1-2-3-7-12-19-18(23)​21-28(26,27)​17-13-15(22(24)​25)​10-11-16(17)​20-14-8-5-4-6-9-14/h10-11,13-14,20H,2-9,12H2,1H3,(H2,19,21,23)​ InCHI Key WNIPBGJWMANRGA-UHFFFAOYSA-N
保存条件: -20°C
说明书地址: 点击查看详细
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