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分子生化试剂 >> 生化试剂 |
Bupropion (hydrochloride)
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产品编号: |
10488-1
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产品名称:
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Bupropion (hydrochloride) .0 订购此产品 |
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供应商:
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Cayman |
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规格: |
1 g |
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目录价: |
1568 |
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库存状态: |
3周 |
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CAS编号:
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31677-93-7 |
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应用范围: |
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种属来源: |
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相关信息: |
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Bupropion (hydrochloride)
Cayman Chemical Item Number 10488
Description
Bupropion is an inhibitor of the reuptake of dopamine and norepinephrine (IC50 = 6.5 and 3.4 μM, respectively).1↗ It is also an antagonist of neuronal acetylcholine nicotinic receptors (nAChR), blocking α3β2 better than α4β2 and α7 (IC50 = 1.3, 8, and 60 μM, respectively).2↗,3↗ As a dual inhibitor of dopamine and norepinephrine reuptake, bupropion is efficacious as an antidepressant.4↗ Because of its effects on nicotinic receptors, it is also used to promote smoking cessation.
Synonyms NSC 315851
Formal Name 1-(3-chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propane, monohydrochloride
CAS Number 31677-93-7
Molecular Formula C13H18ClNO · HCl
Formula Weight 276.2
Formulation A crystalline solid
Purity ≥98%
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES ClC1=CC(C(C(NC(C)(C)C)C)=O)=CC=C1.Cl
InCHI Code 1S/C13H18ClNO.ClH/c1-9(15-13(2,3)4)12(16)10-6-5-7-11(14)8-10;/h5-9,15H,1-4H3;1H
InCHI Key HEYVINCGKDONRU-UHFFFAOYSA-N |
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保存条件: |
-20°C |
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说明书地址: |
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