C-16 Ceramide

产品编号：	10681-25 查看说明书
产品名称：	C-16 Ceramide .0 订购此产品
供应商：	Cayman
规格：	25 mg
目录价：	2695
库存状态：	3周
CAS编号：	24696-26-2
应用范围：
种属来源：
相关信息：
C-16 Ceramide Cayman Chemical Item Number 10681 Description Ceramides are generated from sphingomyelin through activation of sphingomyelinases or through the de novo synthesis pathway, which requires coordinate action of serine palmitoyl transferase and ceramide synthase. They have been shown to mediate antiproliferative responses such as apoptosis, growth arrest, differentiation, and senescence.1↗ C-16 ceramide is an endogenous ceramide, generated by ceramide synthase 6 (CerS6), that acts a lipid second messenger to regulate apoptosis and stress signaling.2↗ Accumulation of C-16 ceramide through PPMP (30 μM) or MAPP (50 μM) treatment or from addition of 100 μM synthetic C-16 ceramide induces apoptosis in neutrophil cultures via caspase-3 activation.3↗ Synonyms Palmitoyl Ceramide Formal Name N-[2R-hydroxy-1S-(hydroxymethyl)-3E-heptadecen-1-yl]-hexadecanamide CAS Number 24696-26-2 Molecular Formula C34H67NO3 Formula Weight 537.9 Formulation A crystalline solid Purity ≥98% Stability 2 years Storage -20°C Shipping Room temperature in continental US; may vary elsewhere SMILES CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC(CCCCCCCCCCCCCCC)=O)CO InCHI Code 1S/C34H67NO3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-33(37)32(31-36)35-34(38)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h27,29,32-33,36-37H,3-26,28,30-31H2,1-2H3,(H,35,38)/b29-27+/t32-,33+/m0/s1 InCHI Key YDNKGFDKKRUKPY-TURZORIXSA-N
保存条件：	-20°C
说明书地址：	点击查看详细

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