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C-6 NBD-dihydro-Ceramide
Cayman Chemical Item Number 10007957
Description
C-6 NBD ceramide is a biologically active fluorescent analog of short chain, membrane-permeable ceramides. It is as effective as C-6 ceramide in the inhibition of viral glycoprotein transport through the Golgi.1↗ C-6 NBD ceramide has been used as a fluorescent substrate for the activity of UDP-glucose:ceramide glucosyltransferase2↗ and to demonstrate the translocation of glucocerebroside and sphingomyelin from the Golgi to the plasma membrane.3↗ C-6 NBD-dihydro-Ceramide is structurally identical to C-6 NBD ceramide, except it contains a saturated bond in the C-4/C-5 position of the sphingosine backbone.
Synonyms N-C6-NBD-D-erythro-dihydro-Sphingosine
Formal Name N-[(1S,2R)-2-hydroxy-1-(hydroxymethyl)heptadecyl]-6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-hexanamide
CAS Number 114301-97-2
Molecular Formula C30H51N5O6
Formula Weight 577.8
Formulation A crystalline solid
Purity ≥98%
λmax 229, 265, 332, 464 nm
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES OC[C@H](NC(CCCCCNC1=CC=C([N+]([O-])=O)C2=NON=C12)=O)[C@@H](CCCCCCCCCCCCCCC)O
InCHI Code 1S/C30H51N5O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-18-27(37)25(23-36)32-28(38)19-16-14-17-22-31-24-20-21-26(35(39)40)30-29(24)33-41-34-30/h20-21,25,27,31,36-37H,2-19,22-23H2,1H3,(H,32,38)/t25-,27+/m0/s1
InCHI Key GEZLBJRDZRUTOE-AHKZPQOWSA-N |