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CAY10510
Cayman Chemical Item Number 10009168
Description
The actions of many clinical prostaglandins, including those used for estrous synchronization and for reduction of intraocular pressure, are mediated through the FP receptor.1↗ CAY10510 is an analog of PGF2α containing an acetylenic fluorobenzene substituent in the lower side chain. CAY10510 has an IC50 of 0.5 µM when tested for binding to the recombinant human FP receptor.2↗
Formal Name 9α,11α,15-trihydroxy-17-fluorophenyl-18,19,20-trinor-prost-16-yn-1-oic acid, methyl ester
CAS Number 291303-34-9
Molecular Formula C24H33FO5
Formula Weight 420.5
Formulation A solution in ethyl acetate
Purity ≥98%
λmax 206, 237, 248, 278, 285 nm
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES FC(C=CC=C1)=C1C#CC(O)CC[C@H]2[C@H](O)C[C@H](O)[C@@H]2CCCCCCC(OC)=O
InCHI Code 1S/C24H33FO5/c1-30-24(29)11-5-3-2-4-9-19-20(23(28)16-22(19)27)15-14-18(26)13-12-17-8-6-7-10-21(17)25/h6-8,10,18-20,22-23,26-28H,2-5,9,11,14-16H2,1H3/t18?,19-,20-,22+,23-/m1/s1
InCHI Key JAQWSGFNEJJFEJ-OCQIDRNCSA-N |