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D-myo-Inositol-1,2-diphosphate (sodium salt)
Cayman Chemical Item Number 10008439
Description
Ins(1,2)P2 (sodium salt) is one of the many inositol phosphate (InsP) isomers that could act as small, soluble second messengers in the transmission of cellular signals.1↗,2↗,3↗ The most studied InsP Ins(1,4,5)P3, is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate.4↗,5↗ Binding of Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium.5↗,6↗ Ins(1,2)P2 (tested as the D/L racemic mixture) is ~1,000-fold less potent than Ins(1,4,5)P3 at initiating Ca2+ release when injected into Xenopus oocytes.7↗
Synonyms Ins(1,2)P2 (sodium salt)
1,2-IP2 (sodium salt)
Formal Name D-myo-inositol-1,2-bis(dihydrogen phosphate), disodium salt
CAS Number 208584-51-4
Molecular Formula C6H12O12P2 · 2Na
Formula Weight 384.1
Formulation A lyophilized powder
Purity ≥98%
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES O[C@@H]1[C@@H](O)[C@@H](OP([O-])(O)=O)[C@@H](OP([O-])(O)=O)[C@H](O)[C@H]1O.[Na+].[Na+]
InCHI Code 1S/C6H14O12P2.2Na/c7-1-2(8)4(10)6(18-20(14,15)16)5(3(1)9)17-19(11,12)13;;/h1-10H,(H2,11,12,13)(H2,14,15,16);;/q;2*+1/p-2/t1-,2-,3+,4+,5?,6?;;/m0../s1
InCHI Key AGYHIHUTKCMLKM-QIYGBPAOSA-L |