OVA peptides InvivoGen provides two standard OVA peptides for detection use (ELISPOT): OVA 257-264 is a class I (Kb)-restricted peptide epitope of ovalbumin (OVA), presented by the class I major histocompatibility complex (MHC) molecule, H-2Kb [1]. It has been demonstrated that OVA 257-264 peptides can be used to detect a strong CD8+ cytolytic T cell response [2]. OVA 323-339 encompasses an allergenic and antigenic epitope of the ovalbumin protein [3]. OVA 323-339 peptide binds to I-A(d) MHC class II protein [4]. OVA 323-339 has been used extensively to study the nature of class II MHC-peptide binding and T-cell activation [5-6]. • OVA 257-264 Description: H-2Kb-restricted OVA class I epitope Sequence: SIINFEKL MW: 963.2 Solubility: 2 mg/ml in water • OVA 323-339 Description: H-2b-restricted OVA MHC class II epitope Sequence: ISQAVHAAHAEINEAGR MW: 1773.9 Solubility: 2 mg/ml in water