E. coli ssDNA / LyoVec

E. coli ssDNA / LyoVec™
E. coli ssDNA is an ultrapure, endotoxin-free preparation of bacterial single-stranded DNA (ssDNA).
It is a better TLR9 ligand than E. coli DNA ef (dsDNA endotoxin-free) as TLR9 binds directly and sequence-specifically to single-stranded unmethylated CpG-DNA.
E. coli ssDNA is complexed with the cationic lipid LyoVec™ to allow a better internalization of the immunostimulatory DNA to the acidic compartment where TLR9 is expressed.
Specificity: TLR9 agonist
Working Concentration: 1 - 10 μg/ml
Endotoxin level:  < 0.001 EU/µg
Solubility: 0.1 mg/ml in water