Pepinh-TRIF TRIF inhibitory peptide Pepinh-TRIF is a 30 aa peptide that blocks TRIF signaling by interfering with TLR-TRIF interaction. PepinhTRIF contains the 14 aa that correspond to the sequence of the BB loop of TRIF (FCEEFQVPGRGELH) [1] linked to the cell-penetrating segment of the antennapedia homoedomain (RQIKIWFQNRRMKWKK) [2]. Pepinh TRIF is provided with Pepinh-Control, a control peptide [1]. Working concentration: 5-50 μM Endotoxin level: <0.125 EU/mg Purity: >95% (HPLC) Species reactivity: Human, mouse Sequences: • Pepinh-TRIF: RQIKIWFQNRRMKWKK-FCEEFQVPGRGELH-NH2 (TRIF homodimerization sequence is underlined) • Pepinh-Control: RQIKIWFQNRRMKWKK-SLHGRGDPMEAFII-NH2 Molecular weights: • Pepinh-MYD: 3918 • Pepinh-Control: 3812