1668 FITC FITC labeled CpG oligonucleotide - Murine TLR9 ligand CpG ODNs are synthetic oligonucleotides that contain unmethylated CpG dinucleotides in particular sequence contexts (CpG motifs). These CpG motifs are present at a 20-fold greater frequency in bacterial DNA compared to mammalian DNA. They have been shown to induce a coordinated set of immune responses based on the activation of immune cells primarily involved in the recognition of these molecules. ODN 1668 FITC is a CpG ODN class B specific for murine TLR9. ODN 1668 FITC can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry. Specificity: murine TLR9 agonist Working concentration: 10 ng -10 μg/ml ODN 1668 sequence 5’-tccatgacgttcctgatgct-3’ (20 mer) Note: Bases are phosphorothioate (nuclease resistant). Spectral Properties of FITC Excitation λ max: 495 nm Emission λ max: 520 nm