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中文名称：胞嘧啶阿拉伯糖苷,盐酸阿糖胞嘧啶, 阿糖胞苷
英文名称:cytrarabine,Ara-C
熔点（℃）:212～213
性状:白色或类白色结晶粉末
溶解情况:溶于水、乙醇、氯仿
用途：主要用于急性白血病：对急性粒细胞白血病疗效最好，对急性单核细胞白血病及急性淋巴细胞白血病也有效。一般均与其他药物合并应用。对恶性淋巴瘤、肺癌、消化道癌、头颈部癌有一定疗效，对病毒性角膜炎及流行性结膜炎等也有一定疗效。
Sigma相关产品资料：
Sigma C1768 Cytosine β-D-arabinofuranoside
crystalline
Synonym: (β-D-Arabinofuranosyl)cytosine, Ara-C, Arabinocytidine, Arabinosylcytosine, Cytarabine, Cytosine arabinoside
CAS Number: 147-94-4
Linear Formula: C9H13N3O5
Molecular Weight: 243.22
Beilstein Registry Number: 89175
EC Number: 205-705-9
MDL number: MFCD00066487
PubChem Substance ID: 24892435
Description
Biochem/physiol Actions Ara-C incorporates into DNA and inhibits DNA replication by forming cleavage complexes with topoisomerase I resulting in DNA fragmentation; does not inhibit RNA synthesis. Anti-leukemia agent.
性质
form crystalline
Gene Information human ... POLB(5423)
mouse ... Cda(72269)
storage temp. 2-8°C |