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Cytochalasin B 细胞松驰素B
Sigma C6762
Cytochalasin B from Drechslera dematioidea
≥98% (HPLC), powder
Synonym: Phomin
CAS Number: 14930-96-2
Empirical Formula (Hill Notation): C29H37NO5
Molecular Weight: 479.61
Beilstein Registry Number: 1096207
EC Number: 239-000-2
MDL number: MFCD00077704
PubChem Substance ID: 24892890
Description
Biochem/physiol Actions One of a group of fungal metabolites that interfere with a wide variety of cellular movements. Useful tool for characterizing some of the polymerization properties of actin,1 and in studies on cytokinesis.2 Probe for the two hexose-transport systems in rat L6 myoblasts.3
Cell permeable fungal toxin that disrupts contractile microfilaments by inhibiting actin polymerization. This, in turn, induces DNA fragmentation, inhibits cell division, and disrupts many cell processes. Inhibits glucose transport.
性质
assay ≥98% (HPLC)
form powder
color white
EQP level Premium
solubility ethanol: soluble20 mg/mL
DMSO: soluble
storage temp. −20°C |